Thursday, October 13, 2011

Unfractionated heparin 1 month

Pulmonary thromboembolism (PTE) is one fatal complications in postoperative patients with ovarian cancer, is also a common cause of sudden death after. PTE thrombus comes mainly from lower limb deep venous thrombosis (DVT), while the DVT and PTE are a total of venous thromboembolism.  United States current research data show that postoperative venous thromboembolic events (VTE) prevention treatment is effective.  United States at Duke University Medical Center Theau (Teoh) by comparing the 5 types of treatment programmes to prevent VTE after found that for abdominal postoperative patients with ovarian cancer, unfractionated heparin (UFH) economic potency than the best treatment 1 month. Study compared the 5 basic prevention and treatment programmes, namely continuous pneumatic compression pump (SCD) therapy, hospital UFH therapy (5000 U, 3 times a day), low molecular weight heparin in the Hospital (LMWH,40 mg/d) therapy, UFH 1 month of therapy (5000 U, 3 times a day, a total of over 1 months) and the LMWH 1 month of therapy (40 mg/d,  Treating 1 month on). Analysis found that UFH 1 month of therapy, average cost is $ 1611, the incidence of VTE is 1.9%, is the 5 kinds of treatment programmes in the least costly and most effective treatment options. LMWH 1 month of therapy have efficiencies and UFH 1 month of therapy are the same (1.9%), but on average more expensive (2,197 dollars).  In addition, the UFH in hospital therapy (5.4%), hospital-LMWH therapy (5.9%) and SCD in hospital therapy (6.4%) is less than the cost of prevention and treatment of UFH 1 month group.  Sensitivity analysis is also prompted, UFH 1 months cost of therapy is ideal, and application of heparin-induced thrombocytopenia costs does not affect the results of this model. Visible for abdominal postoperative patients with ovarian cancer, UFH 1 of VTE after months of therapy is to prevent the most effective and least costly solution. In addition, taking into account the treatment of VTE information that accept LMWH better standards of life in patients with ovarian cancer, the study therefore supports UFH or LMWH 1 month of therapy for prevention of VTE after selecting. www.cmt.com.cn  

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